Diphenidine also known as DPH is among new research chemicals that were created by research chemical manufacturers to learn more about NMDA receptor antagonists that act like an anesthetic chemical. Diphenidine is in the family of drugs known as diarylethylamine. The first mention of this research chemical was in 1924 which was used in laboratories and was used in 1956 to develop phencyclidine.
Chemically diphenidine has a phenethylamine skeleton which is a substitute along with bound at the Ra an extra phenyl ring. The phenethylamine chain has an amino group at the terminal which is incorporated into a piperidine ring. This is what places diphenidine into the family of dissociatives. This compound is an analog of MXP structurally speaking but does not have at the phenyl rings 2-methoxy substitute.
It is believed that diphenidine is an antagonist of the NMDA receptor which means that this research chemical should stop the signals of the NMDA receptors which should produce effects including problems moving and loss of feeling. At this time, more research is needed to determine if diphenidine could be used as an anesthetic. The only research conducted has been on the compound itself and not necessarily the effects, therefore laboratory testing needs to be conducted to learn how the chemical will affect humans. Due to the lack of research, diphenidine is not intended for human consumption.
Some research on diphenidine along with other diarylethylamines showed that this one may produce a stronger effect on the NMDA receptor for neuroprotection, neurological repair, and neurogenesis than others in the same family.
Since there are many research chemicals on the market today, some countries have decided since they are analogs of drugs with high abuse potential they often list the new compounds as well as controlled substances. At this time, the only country that has banned diphenidine is the United Kingdom. It would still be in your best interest to learn if the new research chemical has been listed under your country’s controlled substance list before deciding to do further chemical research.