4F-EPH is a new supplementary research chemical that is in the stimulant family and known to be in the substituted peperidine class and substituted phenidate family. 4F-EPH is an analog of methylphenidate and ethylphenidate due to its closely related structure. 4F-EPH acts very similar to both compounds in laboratory studies, therefore, it is believed to be a double or triple reuptake inhibitor of monoamine. 4F-EPH was developed with the hopes of being an alternative to ethylphenidate also known as Ritalin, to provide a better medication without side effects. However, since the compound was only created in 2016, more research must be done to determine more about how the research chemical works on the brain and body before going to clinical trials.

New research chemicals are developed so further studies can be conducted to discover if there are any benefits that can provide alternatives to medications that are being used for patients with medical or mental issues without the harsh side effects. By using these compounds created from synthetic substances, scientists can learn more about how these research chemicals work in vivo and in-vitro studies. Until more research can be conducted on 4F-EPH it will remain listed with other research chemicals which means it is not intended for human consumption.

What is known about 4F-EPH is that it has a phenethylamine core that has a phenyl ring attached to an amino via an ethyl chain along with a substitution at Ra that is combined with a piperdine ring stopping at the amine terminal of the chain phenethylamine. Along with this, 4F-EPH also has an attachment at R2 with an ethyl acetate and at the phenyl ring, R4 is fluorinated.

It is also believed through studying research chemicals in the same family, that 4F-EPH is more effective as a reuptake inhibitor of dopamine which means it will boost dopamine in the brain as it will bind and block the transporting of proteins so it will accumulate in the brain and bring on euphoric and stimulating effects.