One study conducted on SGT-67 characterized the metabolism as well as the clearance of the research chemical using rat and human liver microsomes along with hepatocytes, which were used to compare to urine sampling and in vivo rat plasma. The study also examined hypothermia. The incubation with the microsomes showed fast metabolic clearance however, in the metabolism in vivo took longer which allowed detection in the rat plasma. The research chemical did show hypothermic effects with 28 metabolites able to be identified.
3-meo-pcp with the formal name of 1-[1-(3-methoxyphenyl)cyclohexyl]-piperidine is classified as a dissociative compound. 3-meo-pcp is an analog of Phencyclidine, which is known as angel dust. 3-meo-pcp binds the NMDA receptor (Ki = 20 nM) and serotonin transporter (Ki = 216 nM) with greater affinity than does PCP (Ki = 59 and 2,234 nM, respectively).
The molecular formula is C18H27NO with a molecular weight of 309.9 and an exact mass of 396.13. 3-meo-pcp is a crystalline solid with a 98% purity.The CAS number for the research compound is 91164-58-8.
Research on 5-eapb was conducted by ACD/Labs’ and US Environmental Protection Agency’s EPISuite, however, no research has been done of 5-EAPB at this time.
5-apb showed 3 #Freely rotating bonds, 2 #H bond acceptors, index of refraction at 1.592, with a flash point of a flash point of 121.377 °C and a boiling point of 277.085 °C at 760 mmHg.